severe craniocerebral injury
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients with traumatic brain injury aged over 18 years; 2.GCS score of 3-12; 3.Patients requiring artificial airway support.
Exclusion criteria
Exclusion criteria: 1.Pregnant patients; 2.Patients with known contraindications to the study drug, such as allergies; 3.Patients with recent frequent use of analgesics, opioid tolerance, or physical dependence; 4.Patients with severe underlying diseases of the heart, lungs, liver, kidneys, or other organs; 5.Patients with psychiatric disorders; 6.Subjects deemed unsuitable for enrollment by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of ventilator;Inhibition of respiratory function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gastric residual volume;PONV degree; | — |
Countries
China
Contacts
Jining NO.1 People’s Hospital