Perioperative myocardial injury
Conditions
Interventions
hyperlipidemia group:Observational study , no intervention
normolipidemia group:Observational study , no intervention
Sponsors
The First People's Hospital of Yibin
Eligibility
Sex/Gender
All
Age
45 Years to 90 Years
Inclusion criteria
Inclusion criteria: (1) Age =45 years (patient more than 45 years is at high risk of developing MINS); (2) Patients with American Society of Anaesthesiologists (ASA) physical condition class I-IV. (3) Patients type: ? Patients with lung cancer (inactive stage) who are scheduled to undergo elective radical tumour surgery. ?Patients with gastrointestinal tumours (inactive) who are scheduled to undergo elective radical tumour surgery. (4) Patients who have signed a consent form to participate in this project.
Exclusion criteria
Exclusion criteria: (1) Patients with increased preoperative troponin I (cTnI); (2) Patients with severe hepatic or renal dysfunction (liver function of Child-Pugh class C or undergoing renal replacement therapy); (3) Patients with preoperative infections: white blood cell count >10×109/L or body temperature >38.3°C; (4) Patients who did not have cTnI measurements preoperatively and did not have cTnI measurements on any of the first three postoperative days; (5) Those with elevated non-ischemic troponin (e.g., suffering from pulmonary embolism, sepsis, cardioversion, congestive heart failure, aortic valve disease, myocarditis, atrial fibrillation); (6) Patients who have not undergone preoperative lipid profile testing; (7) Those with intraoperative haemorrhage or severe drug allergy to shock;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiac troponin;Serum lipid profile;Neutrophil Counts; | — |
Secondary
| Measure | Time frame |
|---|---|
| Interleukin-6;C-reactive protein;white blood cell count;Tumour necrosis factor a; Post-operative hospital stay; | — |
Countries
China
Contacts
Public ContactYang Xue
The First People's Hospital of Yibin
Outcome results
None listed