rectal neuroendocrine tumor
Conditions
Interventions
Traditional ESD:endoscopic submucosal resection
TA-ESD:Traction-assisted endoscopic submucosal resection (TA-ESD)
Sponsors
Shanghai sixth people's hospital
Eligibility
Sex/Gender
All
Age
38 Years to 76 Years
Inclusion criteria
Inclusion criteria: Age: 18-80 years old male/female small rectal neuroendocrine tumor <2cm Preoperative endoscopic ultrasound showed that the tumor was located in the submucosa, did not invade the muscularis propria, and no periintestinal enlarged lymph nodes were found. CT or MRI showed no periintestinal or peritoneal lymphadenopathy and no liver metastases The subjects agreed to undergo endoscopic treatment.
Exclusion criteria
Exclusion criteria: (1) Subject has malignant disease or severe cardiac disease (uncontrolled angina pectoris and/or myocardial infarction, congestive heart failure, etc.) in the 3 months prior to enrollment), lung (respiratory failure) or other diseases judged by the investigator to affect the follow-up evaluation of the study; (2) Subjects have abnormal platelets and coagulation, and have a greater risk of bleeding; (3) Patients who need to continue to use non-steroidal anti-inflammatory drugs, anticoagulants, antiplatelets or Chinese herbal medicine ingredients containing acetylsalicylic acid, ginkgo biloba, and echinacea, and cannot be discontinued due to primary diseases; (4) Preoperative contrast-enhanced CT and endoscopic ultrasound showed lymph node metastasis or distant metastasis around the tumor; (5) Subject is unable to cooperate with endoscopic operations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Operation time; | — |
Secondary
| Measure | Time frame |
|---|---|
| En bloc resection rate;Histological complete resection(R0) rate;days of hospitalization;Complications;Use of antibiotics; | — |
Countries
China
Contacts
Public ContactWan Xinjian
Shanghai sixth people's hospital
Outcome results
None listed