Colorectal Cancer
Conditions
Interventions
High risk/ Medium to low risk/ Positive FIT test/ Negative FIT test:None
Sponsors
Cancer Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
45 Years to 74 Years
Inclusion criteria
Inclusion criteria: 1. Habitant of the study region; 2. Aged 45-74 years old 3. Able to provide informed consent.
Exclusion criteria
Exclusion criteria: 1. Prior history of colorectal cancer 2. Prior history of colonic resection 3. Undertaking any kind of cancer related therapy (Except for non-melanoma skin cancer) 4. Prior colonic examination, including colonoscopy, flexible sigmoidoscopy, CT colonograpy and Barium enema within five years 5. Prior history of fecal occult blood test and fecal DNA test within 1 year 6. Symptoms of lower gastrointestinal tract disease warranting colonoscopic evaluation, including:1)More than one episode of rectal bleeding within the past 6 months; 2) Documented iron deficiency anemia; 3)Significant documented unintentional weight loss (>10% of baseline weight) over 6 months 7.Significant comorbidity that would preclude benefit from screening or pose significant risk for the performance of colonoscopy (e.g. severe lung disease, end-stage renal disease, end-stage liver disease, severe heart failure, recent diagnosis of cancer (with the exception of non-melanoma skin cancer))
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Detection rate of advanced colorectal neoplasm (including colorectal cancer and advanced adenoma);Compliance rate of colorectal cancer screening;Detection rate of any colorectal adenoma; | — |
Secondary
| Measure | Time frame |
|---|---|
| Colorectal cancer incidence;Colorectal cancer mortality; | — |
Countries
China
Contacts
Public ContactMin Dai
Cancer Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed