Effects of accelerated intermittent theta burst stimulation in prolonged disorders of consciousness

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400086727

Enrollment

Unknown

Registered

2024-07-09

Start date

2023-10-06

Completion date

Unknown

Last updated

2024-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

the prolonged disorders of consciousness

Interventions

trail group:accelerated intermittent theta burst stimulation

control group:sham stimulation

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1.Age = 18 years. 2.Stable vital signs. 3.Patients with chronic consciousness disorders: Vegetative State (VS) or Minimally Conscious State (MCS).

Exclusion criteria

Exclusion criteria: 1.Pregnancy. 2.Increased intracranial pressure. 3.Active cerebral hemorrhage. 4.Cranial bone defects in the treatment target area. 5.History of epilepsy or epileptiform activity on electroencephalogram (EEG). 6. Implantation of pacemakers, deep brain stimulators, aneurysm clips, or coronary artery stents.

Design outcomes

Primary

Measure	Time frame
the Coma Recovery Scale –Revised, CRS-R;	—

Secondary

Measure	Time frame
FOUR scores;MBT-r assessment;EEG spectrum;resting fNIRS;GOS-E scores;	—

Countries

China

Contacts

Public ContactZhen Feng

The First Affiliated Hospital of Nanchang University

fengzhenly@sina.com+86 139 7003 8111

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026