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Effect of esketamine combined with dexmedetomidine on postoperative oxygenation index after bedside optic bronchoscopy sputum suction: a prospective, randomised controlled trial.

Effect of esketamine combined with dexmedetomidine on postoperative oxygenation index after bedside optic bronchoscopy sputum suction: a prospective, randomised controlled trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400086719
Enrollment
Unknown
Registered
2024-07-09
Start date
2024-08-01
Completion date
Unknown
Last updated
2024-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pneumonia

Interventions

Group ED:Esketamine combined with dexmedetomidine
Group D:Dexmedetomidine
Control group:Only local anesthesia

Sponsors

The Second Hospital of Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Severe pneumonia patients; 2.ASA III-IV; 3.Age range from 35 to 85 years old.

Exclusion criteria

Exclusion criteria: 1. Preoperative cognitive impairment 2. History of severe hypertension or heart disease 3. There is severe liver and kidney dysfunction Recently taking antidepressants, sedatives, or analgesics 5. Study drug allergies or contraindications 6. Previous history of respiratory surgery 7 failed to complete intraoperative data collection and postoperative follow-up 8. Patient withdrawal or other factors that may affect the experimental results

Design outcomes

Primary

MeasureTime frame
Oxygenation index;—

Secondary

MeasureTime frame
mean arterial pressure, MAP;heart rate, HR;SPO2;—

Countries

China

Contacts

Public ContactLu Zhang

The Second Hospital of Shandong University

sdeyzl@126.com+86 176 6008 1006

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026