Colorectal Cancer
Conditions
Interventions
A:Standard practice whereby no nutritional supplementation is provided.
B:Nestle Isocal is provided. This does not contain any probiotics.
C:Nestle Boost Optimum is provided. This contains probiotics.
Sponsors
NESTLÉ SINGAPORE (PTE) LTD
Eligibility
Sex/Gender
All
Age
21 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients will be eligible to be recruited into the study if they meet all the following inclusion criteria: a. undergoing elective CRC surgery in which an oncologic resection is planned b. age between 21 and 99 years at the time of consent c. willing to consider oral nutritional supplementation d. on our institution’s enhanced recovery after surgery (ERAS) pathway [31] e. able to provide informed consent
Exclusion criteria
Exclusion criteria: Exclusion criteria for this study includes: a. patients with known contraindications to probiotic use b. patients undergoing emergency surgery c. taking any other form of probiotics within one month d. taking oral antibiotics within 7 days of commencement of study e. vulnerable patients including pregnant patients, inmates, and those who are cognitively impaired and therefore are not able to provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to first bowel movement from day of surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to first flatus from day of surgery;Length of hospital stay from day of surgery;Infective complications; | — |
Countries
Singapore
Contacts
Public ContactDedrick Kok Hong Chan
Yong Loo Lin School of Medicine National University of Singapore
Outcome results
None listed