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Effect of nerve blocks combined with different anesthetic depths for use on early cognitive function in older patients undergoing upper limb surgery

Effect of nerve blocks combined with different anesthetic depths for use on early cognitive function in older patients undergoing upper limb surgery

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400086679
Enrollment
Unknown
Registered
2024-07-08
Start date
2024-07-09
Completion date
Unknown
Last updated
2024-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative cognitive dysfunction

Interventions

Brachial plexus block combined with general anesthesia group:General anesthesia was performed after the completion of the brachial plexus block(BIS40-60)
Brachial plexus block combined with deep sedation group:Deep sedation was performed after brachial plexus block
Brachial plexus block combined with mild sedation:Mild sedation was performed after brachial plexus block

Sponsors

Yibin Second People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) Elderly patients who underwent elective unilateral upper limb surgery in our hospital from July 2022 to June 2024; (2) Age: 60 years, 18 kg/m 2 <BMI <30 kg / m 2, ASA grade I-III; (3) Anesthesia monitoring time is 2-3 hours; (4) preoperative cognitive function is normal and no use of psychotropic drugs;

Exclusion criteria

Exclusion criteria: (1) History of neurological illness or mental illness (such as Alzheimer's disease, stroke, or depression); (2) Currently taking anti-anxiety, depression drugs and other psychotropic drugs; (3) The infected persons at the block site and other anesthesia contraindications; (4) History of alcohol abuse; (5) Severe auditory or visual impairment existed before surgery.

Design outcomes

Primary

MeasureTime frame
bispectral index;Mona1 c0tiVe sessment;Visual analogue score;Hamilton Anxiety Scale;

Countries

CHINA

Contacts

Public ContactCHEN HUI

Yibin Second People's Hospital

ch13696038855@163.com+86 135 1848 5230

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026