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Effect of budesonide combined with pulmonary surfactant on lung development in very low birth weight infants

Effect of budesonide combined with pulmonary surfactant on lung development in very low birth weight infants

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400086677
Enrollment
Unknown
Registered
2024-07-08
Start date
2024-08-01
Completion date
Unknown
Last updated
2024-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bronchopulmonary dysplasia

Interventions

1 Budesonide suspension + pulmonary surfactant:None
2 Pulmonary surfactant:None

Sponsors

Second Hospital of Jilin University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 1 Years

Inclusion criteria

Inclusion criteria: (1) Patients with severe NRDS requiring mechanical ventilation within 4h after birth; (2) The initial demand for inhaled oxygen concentration = 40%.

Exclusion criteria

Exclusion criteria: (1) Postnatal asphyxia, with or without organ injury; (2) Combined with surgical disease or congenital heart disease; (3) Congenital genetic metabolic disease.

Design outcomes

Primary

MeasureTime frame
Ventilator use time;Oxygen requirement duration;Bronchopulmonary dysplasia;—

Secondary

MeasureTime frame
Intracranial hemorrhage;Retinopathy prematurity;Neonatal infection;Necrotizing enterocolitis of the newborn;—

Countries

China

Contacts

Public ContactZhang Yunfeng

Second Hospital of Jilin University

Yunfengzhang11@126.com+86 431 8113 6949

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026