end-stage renal disease
Conditions
Interventions
Hydroxyethyl Starch Group (HES group):Intraoperative use of low molecular weight hydroxyethyl starch and crystalloid solution
Crystalloid group (CRYS group):Intraoperative exclusively infused with crystalloid solution
Sponsors
The First Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients who were 18 years or older, diagnosed with end-stage kidney disease, and scheduled for donation-after-cardiac-death kidney transplant under general anesthesia
Exclusion criteria
Exclusion criteria: 1) multiple kidney transplants, 2) combined multiorgan transplant, 3) use of hydroxyethyl starch only after surgery, 4) undergoing an additional surgical procedure within 7 days following the initial surgery, 5) missing primary outcome.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of DGF; | — |
Secondary
| Measure | Time frame |
|---|---|
| Need for dialysis 30 days postoperatively;Acute rejection within 30 days after surgery;Serum creatinine;eGFR;BUN;Serum cystatin C;Incidence of vascular and ureteral complications in the transplanted kidney within 30 days after surgery;Allograft survival at 1 year postoperatively;Overall survival at 1 year postoperatively;Length of hospital stay;the incidence of intraoperative hypotension;the incidence of intraoperative bradycardia;use of dopamine during the surgery; | — |
Countries
China
Contacts
Public ContactXi-Sheng Shan
The First Affiliated Hospital of Soochow University
Outcome results
None listed