Impacted tooth, jaw fracture
Conditions
Interventions
Esketamine combined with sufentanil group:Esketamine combined with sufentanil is used for intravenous patient-controlled analgesia pump, with the formula of the analgesia pump being sufentanil 1.5µg/k
Sufentanil group:Sufentanil is used for intravenous patient-controlled analgesia pump, with the formula of the analgesia pump being sufentanil 2µg/kg plus palonosetron 0.5mg, diluted to 100ml with nor
Sponsors
First People's Hospital of Lianyungang
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patient age between 18 to 75 years old; 2. Patients scheduled for elective oral surgery; 3. BMI between 18 to 30 kg/m²; 4. ASA I to III; 5. Fully understand and voluntarily participate in this study, and have signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Allergic to the experimental drug; 2. Patients with unstable ischemic heart disease, severe pulmonary hypertension, poorly controlled or untreated hypertension; 3. At serious risk of increased intracranial or intraocular pressure; 4. A history of untreated or undertreated hyperthyroidism or epilepsy; 5. Long-term use of non-steroidal anti-inflammatory drugs, opioids, sedatives; 6. Any history or treatment of neurological or psychiatric disorders, including substance abuse, anxiety, or depression; 7. Vital organ dysfunction, liver dysfunction, renal dysfunction; 8. Those who do not agree or are unable to use intravenous patient-controlled analgesia (PCIA) pumps.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ramsay sedation score;QoR-15 score;Incidence of Drug-Related Adverse Reactions;The Use of Sufentanil within 48 Hours Post-Surgery;Pain Relief Satisfaction Score; | — |
Countries
China
Contacts
Public ContactYing Chen
First People's Hospital of Lianyungang
Outcome results
None listed