depression and anxiety disorder
Conditions
Interventions
Gold Standard:Meets the diagnostic criteria for depression or generalized anxiety disorder in DSM-5
Index test:Multi-modal data fusion of traditional Chinese and western medicine is used to objectively diagnose depression and anxiety: Chinese medicine's sight, smell, question and pulse are based on
Western medicine: brain functional imaging acquisition: resting-state functional magnetic resonance imaging (rsfMRI), task-state functional magnetic resonance imaging (tfMRI), near-infrared brain func
Sponsors
Huzhou Third People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: The criteria for patients in the disease group include: ? Patients with depression, anxiety, and depression complicated with anxiety assessed by SCID by a psychiatrist trained in depression and anxiety research and a senior psychiatrist; ? Meet the diagnostic criteria of depression or generalized anxiety disorder in DSM-5; ?HAMD- 24 score =17 or HAMA- 14 score =14; ? The age is 18 ~ 60 years; ? The current course of disease (last onset) is at least 2 weeks; ? No electroconvulsive therapy was given in the first half year; ? Being conscious and communicating smoothly, voluntarily participating and signing the informed consent form; ?Being right-handed. The criteria for admission to the control group include: ? Aged from 18 to 60; ?HAMD-24 score < 7, HAMA-17 score < 7; ? No serious physical illness, no history of mental illness, alcohol and drug abuse; (4) conscious, smooth communication, voluntary participation and signed informed consent; ? Right-handed.
Exclusion criteria
Exclusion criteria: Exclusion criteria for patients in disease group include: (1) combined with another mental illness; ? Have a history of alcohol/drug dependence or smoke more than 10 cigarettes/day; ? Serious somatic diseases of heart, liver, kidney, brain and hematopoietic system, central nervous system infection, head injury, epilepsy, multiple sclerosis, toxic metabolic diseases, Parkinson's disease or intracranial tumors; ? Family history of hereditary diseases; ? Endocrine diseases such as diabetes, hyperthyroidism or hypothyroidism; ? Pregnant and lactating women or people who are allergic to light. Exclusion criteria of control group: (1) those who have a family history of mental illness within two families and three generations; ? Pregnant and lactating women or people who are allergic to light.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eye movement index;EEG index;specificity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate variability;sensitivity; | — |
Countries
China
Contacts
Public ContactZhongxia Shen
Huzhou Third People's Hospital
Outcome results
None listed