chronic atrophic gastritis/ gastroesophageal reflux disease
Conditions
Interventions
CAG group (Part 2):Granule (Banxiaxiexin formula)
GERD group (Part 2):Granule (Banxiaxiexin formula)
CAG group (Part 1):None
GERD group (Part 1):None
Sponsors
Wangjing Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria of patient cases 1.Meets diagnostic criteria for both Chinese and Western medicine, 2.The patents are between 18 and 70 years old, 3. The patents are voluntarily participated and signed the informed consent form. Inclusion criteria of healthy volunteers 1.No chronic gastrointestinal disease, no history of circulatory, respiratory and urinary diseases, 2.Blood routine, urine routine, stool routine, liver and kidney function, and electrocardiogram were normal, 3. The healthy volunteers are between 18 and 70 years old, 4.They did not take any medicine before the physical examination, 5.The healthy volunteersare voluntarily participated and signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Autoimmune gastritis; 2. Gastric mucosa with high-grade intraepithelial neoplasia or suspected malignant transformation by pathological diagnosis; 3. Patients with serious primary diseases such as heart, brain, liver, kidney, lung and blood system; 4. Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pepsinogen I;propepsin ?;Gastrin 17;Pepsinogen ratio;Psychometric scale;SF-36 Quality of Life Scale;Traditional Chinese medicine syndrome score scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Interleukin-1;Interleukin-6;Interleukin-8;Tumour necrosis factor;The gastrointestinal hormone somatostatin;gastrin;cholecystokinin;Helicobacter pylori IgG antibody;Substance P;calcitonin generelated peptide;Blood routine examination;Urine routine examination;Liver function examination;Renal function examination; | — |
Countries
China
Contacts
Public ContactAili Xu
Wangjing Hospital, China Academy of Chinese Medical Sciences
Outcome results
None listed