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Feasibility and safety of remazolam combined with sufentanil in laryngeal mask anesthesia without neuromuscular block: a single-center, prospective, randomized controlled study

Feasibility and safety of remazolam combined with sufentanil in laryngeal mask anesthesia without neuromuscular block: a single-center, prospective, randomized controlled study

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400086601
Enrollment
Unknown
Registered
2024-07-08
Start date
2024-07-09
Completion date
Unknown
Last updated
2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

minor surgical procedure

Interventions

Remazolam group:Anesthesia was induced by intravenous remazolam and sufentanil
Propofol group:Anesthesia was induced by intravenous propofol and sufentanil

Sponsors

Weihai Municipal Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: ? Elective surgery, and the operation time<2 hours; ? Age 18-65 years old; BMI 18-28kg/m2 ? ASA grade I - ? ? sign the informed consent

Exclusion criteria

Exclusion criteria: ? Those with clinical symptoms of cardiovascular and respiratory diseases or liver and kidney diseases; ? Severe hypertension and diabetes; ? Combined with central nervous system disease; ? Difficult airway; ? Allergic to the investigational drug

Design outcomes

Primary

MeasureTime frame
The primary outcome of this study was the summed scores of the LMA insertion conditions.;

Secondary

MeasureTime frame
The number of successful insertion attempts and the tidal volume and airway pressure of patients after LMA insertion were recorded;Patient's systolic blood pressure, diastolic blood pressure, mean blood pressure, herat rate;The injection pain, hiccups, laryngeal spasms and nausea and vomiting after awakening were recorded;Patient resuscitation time and RAAS score after resuscitation(evaluation for sedation-agitation with a score ranging from -3 to + 3,0 being fully awake);

Countries

China

Contacts

Public ContactDu Shuping

Weihai Municipal Hospital

dsping0105@126.com+86 132 8784 3388

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026