Painless abortion
Conditions
Interventions
Propofol Group:Different dose of propofol with 0.15 mg/kg esketamine. The dose for the subsequent patient in the study was based on the response of the preceding patient
Ciprofol Group:Different dose of ciprofol with 0.15 mg/kg esketamine. The dose for the subsequent patient in the study was based on the response of the preceding patient
Sponsors
INTERNATIONAL PEACE MATERNITY & CHILD HEALTH HOSPITAL
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: aged 18-45 years BMI within 18.5-28 kg/m2 Modified Mallampati Grades I or II American Society of Anesthesiologists (ASA) Grades I or II undergoing painless abortion
Exclusion criteria
Exclusion criteria: ASA physical status Grade III or IV baseline oxygen oximetry (SpO2) < 95%, comorbidities such as diabetes mellitus, hypertension (HTN), hepatic or renal insufficiency, obstructive sleep apnea syndrome a known allergy to anesthesia drugs, and a history of egg or soya bean allergy Patients who had consumed solid food in the last eight hours or clear liquid food in the last four hours Patients who refused to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| patient movement within 5 min after the painless abortion surgery began; | — |
Secondary
| Measure | Time frame |
|---|---|
| respiratory pause;SpO2 < 95%;injection pain;heart rate;blood pressure;respiratory rate;salivation;Dizziness;Fatigue;Psychoactive effects;pain numerical rating scale;Aldrete score; | — |
Countries
China
Contacts
Public ContactYe Shanshan
INTERNATIONAL PEACE MATERNITY & CHILD HEALTH HOSPITAL
Outcome results
None listed