lung Cancer
Conditions
Interventions
Test group:Intravenous infusion of magnesium sulfate 50mg/kg before anesthesia induction
Control group:None
Sponsors
Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing video-assisted thoracoscopic lobectomy with general anesthesia; 2. Age 18-65 years old; 3.American Society of Anesthesiologists Physical Status Classification grade I - III; 4.BMI 18-30 kg/m2.
Exclusion criteria
Exclusion criteria: 1. History of mental illness or cognitive dysfunction; 2. Bradycardia and atrioventricular block; 3. preoperative electrolyte disorder; 4. Neuromuscular system diseases; 5. Severe cardiovascular and cerebrovascular diseases, liver, lung and kidney diseases (BUN > 7.5 mmol/L; Scr>110µmol/L); 6. Use polymyxin B sulfate, streptomycin sulfate, calcium gluconate, dobutamine hydrochloride, procaine hydrochloride, penicillin and naftoxacillin (ethoxy) antibiotics; 7. History of drug abuse; 8. Allergy to the drugs involved in this study; 9. Have participated in other clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of emergence agitation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative recovery quality;Extubation time;Postoperative VAS score;Postoperative adverse events;Incidence of rescue analgesia;Usage of analgesic pump within 24 hours after operation; | — |
Countries
China
Contacts
Public ContactChen Xiuxia
Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed