Cough after infection with novel coronavirus
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Age range: 18 to 70. 1, the patient had a history of coronavirus infection, and the patient was positive for nucleic acid or antigen test, 2, the acute symptoms of coronavirus infection, such as fever and pain, had disappeared, and the cough symptoms were still delayed for more than 8 weeks, 3, chest X-ray or chest CT and other imaging examination can not be obvious, significantly abnormal; 4, blood routine showed that the patient's total white blood cells, classification in the normal range; 5, need to exclude other causes of chronic cough.
Exclusion criteria
Exclusion criteria: Viral myocarditis or cardiac insufficiency: for the elderly or those with cardiovascular disease, once cough, obvious at night, supine position aggravates, need to consider the possibility of cardiac insufficiency. In addition to cough symptoms, patients often accompanied by breathing, difficulty of the performance, both lung bottom can smell wet Rales, combined with the basic disease history, chest imaging, ECG, myocardial zymogram, cardiac ultrasound and brain natriuretic peptide (BNP-RRB- examination. When necessary, experimental anti-heart failure treatment, observation of cough, cough relief to identify. Exacerbation of the underlying disease: after covid-19 infection, lung cancer, bronchiectasis, asthma and COPD can become acute exacerbations, leading to prolonged coughing. Patients often have a clear history of chronic airway disease, in addition to cough, often have other basic clinical features of the disease, combined with chest imaging and pulmonary function tests are not difficult to identify. Others: such as covid-19 infection caused by hypercoagulable state of pulmonary embolism, can be manifested as cough, chest pain, breathing difficulties, and hypoxemia, need close attention. Patients with stroke, myocardial infarction, abnormal blood coagulation, severe anxiety and depression, complicated with severe hematological diseases, abnormal blood coagulation and hemoglobin lower than 75g/l; Patients with severe diabetes mellitus or heart, liver and kidney insufficiency; patients with systemic infection; those who did not want to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TCM syndrome integral;coughevaluation test; Pulmonary function test;Anxiety and depression scores; | — |
Countries
CHINA
Contacts
Fuyang Hospital of Anhui Medical University