Pediatric strabismus surgery and anesthesia
Conditions
Interventions
Midazolam group:3min before anesthesia induction, midazolam group was given 0.1mg/kg intravenous slow injection
Dexmedetomidine group:3min before anesthesia induction, dexmedetomidine group was given 1ug/kg intravenous slow injection
Sponsors
Xuzhou First People's Hospital
Eligibility
Sex/Gender
All
Age
2 Years to 7 Years
Inclusion criteria
Inclusion criteria: (1) ASA is grade I ~ II; (2) Age 2-7 years old; (3) Elective strabismus surgery was proposed.
Exclusion criteria
Exclusion criteria: (1) Severe comorbidities of ASA grade III and above; (2) Allergic to dexmedetomidine or midazolam; (3) Use of preoperative sedatives on the day of surgery; (4) The operation time is less than 10 minutes or more than 60 minutes; (5) Existing behavioral problems (treated by a pediatrician for behavioral problems or currently on medication for behavioral problems such as attention deficit, hyperactivity disorder, etc.); (6) Have mental health problems (autism, anxiety, etc.) or take psychiatric drugs before surgery; (7) Family members or guardians refuse to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative 3d adverse behavior change; | — |
Secondary
| Measure | Time frame |
|---|---|
| Wake delirium score (PAED score);Incidence of adverse behavior changes at 1d, 7d and 28d after surgery;EEG characteristics of children during operation and after recovery;Postoperative Pain Score (FLACC Score);Incidence of other adverse events (allergies, nausea, vomiting, chills);Recovery time and postoperative hospital stay;Parental satisfaction; | — |
Countries
China
Contacts
Public ContactBizhao Dai
Xuzhou First People's Hospital of Jiangsu Province
Outcome results
None listed