Skip to content

A study of the therapeutic efficacy of intramedullary infusion aspiration (RIA) versus autologous iliac bone grafting (ICBG) for the treatment of defects

A study of the therapeutic efficacy of intramedullary infusion aspiration (RIA) versus autologous iliac bone grafting (ICBG) for the treatment of defects

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400086488
Enrollment
Unknown
Registered
2024-07-02
Start date
2024-07-10
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bone defect

Interventions

RIA group:Extraction of autogenous bone from the femur using a marrow expansion-perfusion-aspiration system
ICBG group:Treatment of bone defects using conventional surgery to remove bone tissue from the patients iliac bone

Sponsors

Department of Orthopaedics, Tang Du Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: ? Patients aged 18-60 years who are eligible to participate in the study and are able to sign the informed consent form. ? Patients with segmental bone defects and focal bone defects; patients with segmental bone defects that are more than 1.5 times the diameter of that tubular bone and planned for segmental bone grafting. ? Patients with pre-existing infections also included, but the infection was controlled at the time of inclusion.

Exclusion criteria

Exclusion criteria: ? Patients with any previous injury to the donor site femur or iliac crest that prevented harvesting were excluded. ? Previous fractures of the iliac wing and proximal femur and other lesions were excluded.

Design outcomes

Primary

MeasureTime frame
Clinical and Imaging Healing;

Secondary

MeasureTime frame
Osteogenic capacity;Surgery-related indicators: time to remove bone, bleeding, cost of surgery and other indicators;Evaluation of limb function;

Countries

China

Contacts

Public ContactYunfei Zhang

Tang Du Hospital

tdbone@163.com+86 135 7288 2092

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026