Effect of Acupuncture on IVF-ET Pregnancy Outcomes in Patients with Poor Ovarian Response (POR)

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400086485

Enrollment

Unknown

Registered

2024-07-02

Start date

2024-07-09

Completion date

Unknown

Last updated

2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Poor ovarian response

Interventions

Acupuncture group:Acupuncture plus microstimulation protocol for ovulation induction

Sham acupuncture group:Sham acupuncture plus microstimulation protocol for ovulation induction

Control group:Microstimulation protocol for ovulation induction

Eligibility

Sex/Gender

Female

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: ? Patients with POR who meet Bologna diagnostic criteria. ? No traditional Chinese medicine, acupuncture and ovarian hyperstimulation treatment were performed in the past 3 months. ? Blood TORCH, syphilis antibody and hepatitis B antibody showed no obvious abnormality, except infectious factors; sex hormone and thyroid function showed no obvious abnormality, except endocrine factors; autoantibody examination except autoimmune factors; B ultrasound and hysteroscopy except reproductive organ anatomical factors; ? The semen examination of the husband showed no obvious abnormality; ? The karyotype of couples is normal, except for genetic factors; ? Signed informed consent after understanding the study process.

Exclusion criteria

Exclusion criteria: ? Hydrosalpinx, congenital uterine malformation or endometrial disease, such as tuberculosis or hyperplasia; ? Basal follicle-stimulating hormone (bFSH) level = 15 IU/L; ? Systemic lupus erythematosus, Sjogren's syndrome or polycystic ovary syndrome; ? Endocrine disorders, such as diabetes mellitus, hyperthyroidism, hypothyroidism or hyperprolactinemia; ? Intracytoplasmic sperm injection caused by male infertility; ? Patients with severe hypertension, liver and kidney function damage, mental illness that can not cooperate with the treatment; ? Patients with coagulopathy who cannot be treated with acupuncture and moxibustion.

Design outcomes

Primary

Measure	Time frame
Clinical pregnancy rate;	—

Secondary

Measure	Time frame
Embryo-related indicators;Oxidative stress-related indicators;	—

Countries

China

Contacts

Public ContactXin Lai

Department of Traditional Chinese Medicine, Sixth Affiliated Hospital of Sun Yat-sen University

laix6@mail.sysu.edu.cn+86 155 2124 7966

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026