Coronary heart disease/Cardiovascular disease
Conditions
Interventions
Intervention group:The CR programme involves home-based training in which participants were supplied with a heart rate belt to wear while exercising and download a smartphone application (app) called
Control group:The control group did not carry out home rehabilitation exercise, and the baseline cardiopulmonary function and physical function status indexes were evaluated in the rehabilitation depa
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: To be eligible to participate in this study, a subject must meet all of the following criteria: Aged 18-65 years with diagnosed with CHD by coronary angiography and completed PCI; Classified I–III under the New York Heart Association classification of cardiac function; Hemodynamic stability with stable vital signs (defined as mean arterial pressure 60-100mmHg; unoxygenated SpO2 =88%; resting heart rate 60-120 bpm); Signed written informed consent.
Exclusion criteria
Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from this study: Diagnosed as hypertrophic obstructive cardiomyopathy, decompensated heart failure or unstable angina pectoris; Diagnosed as bradycardia (heart rate =50 bpm), Grade II or III atrioventricular block, sick sinus syndrome, Adams-Stokes syndrome, fast ventricular fibrillation or other exercise-induced arrhythmia at screening; Diagnosed as severe pulmonary dysfunction (defined as FEV1< 40% predicted, and FEV1/FVC <50% predicted); Expected survival to be < 6 months; Suffered severely impairement of activity tolerance(<2 METs); No access, availability or insufficient knowledge of a mobile phone with Internet; Enrolled or participated in other trials within the past 3 months.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| The parameters of mitochondria metabolism from stress test;Other parameters obtained from CPET ;Maximum inspiratory and expiratory muscle strength;several validated questionnaires to assess their general health condition;inflammatory biomarkers; | — |
Primary
| Measure | Time frame |
|---|---|
| The primary outcome (VO2peak) was measured by CPET ; | — |
Countries
China
Contacts
Public ContactQuan Wei
West China Hospital of Sichuan University
Outcome results
None listed