Effect of anesthesia depth dual parameter (IoC) monitoring on the dosage of propofol and remifentanil in total intravenous anesthesia for patients undergoing knee arthroscopy

Effect of anesthesia depth dual parameter (IoC) monitoring on the dosage of propofol and remifentanil in total intravenous anesthesia for patients undergoing knee arthroscopy - Anesthesia depth dual parameter (IoC) monitoring

Status

Active, not recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2400086467

Enrollment

Unknown

Registered

2024-07-02

Start date

2022-12-01

Completion date

Unknown

Last updated

2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

17. Meniscus injury

Interventions

Contral :No dual parameter monitoring of anesthesia depth

Observation group:dual parameter monitoring of anesthesia depth:index of consciousness combined the injury sensitivity index(IoC)

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: ? Age >18 years old; ? American Society of anesthesiologists anesthesia classification I-II; ? Unilateral knee arthroscopic meniscus surgery; ? Body mass index (BMI) is 18 ~ 30kg / m2; ? The functions of heart, liver, kidney and lung are basically normal; No anemia; ? Knee arthroscopic meniscus surgery under total intravenous anesthesia; ? Complete case data.

Exclusion criteria

Exclusion criteria: ? Severe anemia; ? People who are allergic to opioids or propofol, remifentanil, etc; ? Have a history of acute and chronic respiratory system; ? Cardiovascular disease or mental disease; ? Organic dysfunction of heart, liver, kidney and lung; ? Abnormal hearing; ? Pregnant or lactating women; ? Bmi>30 kg / m2; ? Incomplete clinical data.

Design outcomes

Primary

Measure	Time frame
Dosage of propofol and remifentanil;Dual parameter monitoring of anesthesia depth;	—

Secondary

Measure	Time frame
Twelve cytokines expression;Perioperative vital signs;VAS;	—

Countries

China

Contacts

Public ContactFang Xie

Shanghai Sixth People's Hospital

fyyxz2015@163.com+86 158 2169 5291

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026