acute respiratory distress syndrome
Conditions
Interventions
Experiment group:Sivelestat sodium was given on the basis of treatment in the Control group
Control group:Non invasive mechanical ventilation treatment
Sponsors
Hai'an People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Acute lung injury conformed to the criteria established by the Chinese Medical Association in 2006. (2) Age =18 years, =65 years, no gender restriction. (3) Good compliance with treatment and efficacy evaluation
Exclusion criteria
Exclusion criteria: (1) Shock or solid malignancy. (2) Upper respiratory tract injury. (3) Severe cardiac, hepatic and renal dysfunction. (4) Hypersensitivity to sevastatin sodium. (5) Pregnancy, pregnancy preparation, breastfeeding. (6) Blood and immune system diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maximum ventilation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mechanical ventilation time;ICU hospitalization time;case fatality rate;lung function;tumor necrosis factor-a;Interleukin-1ß;Intercellularadhesionmolecule-1; nucleotide-binding oligomerization domain-like receptor protein-6;oxygenation index;respiratory rate; | — |
Countries
China
Contacts
Public ContactYaqing Zhou
Hai'an People's Hospital
Outcome results
None listed