Gynecological disease
Conditions
Interventions
Remazolam group:Remazolam was administered intravenously after admission.The initial dose was 0.2mg/kg.To observe whether the consciousness disappeared within 1min after remazolam administration.The n
Remazolam combined with music therapy group:Patients were given music of their choice for 5 minutes and then remazolam was injected intravenously.To observe whether the consciousness disappeared withi
Sponsors
Fuyang Hospital of Anhui Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients who planned to undergo gynecological hysteroscopic surgery were classified as ASA grade I-II; 2. Age 18-60 years old; 3. BMI18-30kg/m²; 4. Normal communication; 5. Volunteer to be tested and sign informed consent
Exclusion criteria
Exclusion criteria: 1. Serious respiratory and circulatory diseases: such as serious coronary heart disease, COPD, etc.; 2. Endocrine system diseases: pituitary tumor, severe diabetes, increased cortisol, pheochromocytoma, etc.; 3. Mental illness: such as schizophrenia, depression, chronic analgesic drug use history, alcoholism history, opioid dependence; 4. Intellectual disability, sleep disorder, consciousness dysfunction, etc. 5. Known to be allergic to experimental drugs and other drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sequential results of loss of consciousness induced by remazolam and corresponding dose; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure and heart rate;Bispectralindex (BIS);Respiratory rate;Blood Oxygen saturation;Occurrence of respiratory depression;Occurrence of nausea and vomiting; Perioperative adverse events;The Modified Observer’s Assessment of Alertness and Sedation scale; | — |
Countries
China
Contacts
Public ContactJinpeng Zhang
Fuyang Hospital of Anhui Medical University
Outcome results
None listed