Partial hepatectomy
Conditions
Interventions
Remazolam combined with propofol group:Anesthesia induction: After full oxygenation and denitrification, patients were slowly injected with Sufentanil 0.3-0.4 µg/kg, remazolam 0.1mg /kg+ propofol 0.5-
RP group: intravenous pump remazolam 0.2-0.4 mg/(kg·h), propofol 1-4 mg/(kg·h)
At the end of the operation, patients in the RP group were given intravenous flumazenil 0.5 mg.
Propofol group:Anesthesia induction: After full oxygenation and denitrification, patients were slowly injected with Sufentanil 0.3-0.4 µg/kg, propofol 1-2.5 mg/kg (group P), and cisatracurium 0.15 mg/
Group P: intravenous pump propofol 2-8 mg/(kg·h)
At the end of the operation, patients in the P group were given intravenous saline of the same amount.
Sponsors
Affiliated Hospital of North Sichuan Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Adult patients were selected for elective laparoscopic liver resection under general anesthesia, regardless of gender, age 18-80 years, BMI 18.5 ~ 28.0 kg/m^2, ASA II or III, and the expected time of surgery was 2 ~ 4 h
Exclusion criteria
Exclusion criteria: ? Complicated with severe kidney, heart and other organ dysfunction; ? Severe diseases of respiratory system, metabolic system and immune system; ? Coagulation function, neurological function, cognitive function impairment; ? History of allergic or adverse reactions to narcotic drugs used in this study; ?Unable to understand the written information or informed consent of the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time for patient to follow instructions (starting from the end of the procedure when the medication is stopped); | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of CSI over 80 ; | — |
Countries
China
Contacts
Public ContactFeng Yan
Affiliated Hospital of North Sichuan Medical College
Outcome results
None listed