periodontitis
Conditions
Interventions
Bone resorption to 3-6 mm from the root apex:NA
Bone resorption to 0-3 mm from the root apex:NA
control group of experiment ?:NA
Bone resorption to 3-6 mm from the root apex and taking root canal treatment:NA
extracted teeth because of severe periodontitis:none
control group of experiment ?:none
Sponsors
Hospital of Stomatology, China Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Experiment ?: (1) Age 18-70 years. (2) No systemic diseases such as hypertension, heart disease, diabetes mellitus. (3) No antibiotics, anti-inflammatory drugs or other medications that may affect periodontal tissues within 6 months. (4) Severe periodontitis (Stage III or IV). (5) The affected teeth are a single rooted teeth. (6) The CBCT images of affected teeth show alveolar bone resorption to =6 mm from the root apex. (7) The affected teeth have no history of previous endodontic treatment and no history of periodontal treatment within 1 year. (8) Informed consent. Experiment ?: (1) The affected teeth appear to be abnormal in pulp vitality test or with endodontic symptoms. (2) The rest of the inclusion criteria are the same as experiment ?. Experiment ?: (1) The affected teeth that cannot be retained due to severe periodontitis. (2) The healthy teeth are extracted for orthodontic reasons, without dental or periodontal diseases and with intact dental tissues. (3) The rest of the inclusion criteria are the same as experiment ?.
Exclusion criteria
Exclusion criteria: Experiment ?: (1) The affected teeth have dental disorders such as caries, fillings, incomplete fracture, and heavy abrasion. (2) The affected teeth have developmental malformations such as dens invaginatus and palato-gingival grooves. (3) The affected tooth has dental trauma, primary occlusal trauma, secondary occlusal trauma, or is undergoing orthodontic treatment. (4) Patients with acute inflammation, infection, oral mucosal disease or trauma. (5) Smoking or quit smoking for less than 5 years. (6) Pregnant or breastfeeding women. Experiment ?: (1) The affected teeth with imperfect root canal treatment. (2) The rest of the exclusion criteria were the same as in experiment ?. Experiment ?: (1) The affected teeth with crown fracture, root fracture or tooth defects during extraction. (2) The rest of the exclusion criteria were the same as in experiment ?.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| probing depth;clinical attachment loss;tooth mobility;pulpal state; | — |
Secondary
| Measure | Time frame |
|---|---|
| bleeding on probing;plaque index; | — |
Countries
China
Contacts
Public ContactLi Chen
Hospital of Stomatology, China Medical University
Outcome results
None listed