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Application of indocyanine green fluorescence imaging-guided laparoscopic left-sided colorectal cancer surgery in assessment of anastomotic blood perfusion: a prospective, single center and randomized controlled trial

Application of indocyanine green fluorescence imaging-guided laparoscopic left-sided colorectal cancer surgery in assessment of anastomotic blood perfusion: a prospective, single center and randomized controlled trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400086411
Enrollment
Unknown
Registered
2024-07-01
Start date
2022-01-18
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal cancer

Interventions

control group:traditional (robot assisted) laparoscopic left-sided colorectal cancer surgery.
experimental group:indocyanine green fluorescence imaging-guided (robot assisted) laparoscopic left-sided colorectal cancer surgery

Sponsors

The Third Xiangya Hospital of Central South University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Range 18-80 years of age, (2) preoperative pathological diagnosis of colorectal cancer; (3) undergoing elective laparoscopic left colon or rectal cancer resection with one-stage anastomosis; and (4) clinical stage TNM stages I-III: cT1-4, N0-2, M0 (AJCC - 8 version).

Exclusion criteria

Exclusion criteria: (1)Allergy to ICG or iodine, (2)Patients with severe ileus, intestinal perforation, intestinal bleeding requiring emergency surgery, (3)Patients with tumor involvement of adjacent organs requiring combined resection, (4)Patients with distant metastases or tumor recurrences, (5)Patients with multiple colorectal tumors, (6)Patients with tumors 12 points.(12)Patients with renal dysfunction (creatinine =2.0 mg/dL).

Design outcomes

Primary

MeasureTime frame
the rate of anastomotic leakage;

Secondary

MeasureTime frame
other complications;Operation time;Postoperative hospitalization days ;

Countries

China

Contacts

Public ContactGui Hu

Department of Gastrointestinal Surgery, The Third Xiangya Hospital of Central South University

hugui22@csu.edu.cn+86 137 8720 9450

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026