Muscle damage and oxidative stress
Conditions
Interventions
Blueberry Polyphenol Group:4.7 g of blueberry polyphenols (polyphenols 1212.13 mg, anthocyanins 296.1 mg) per day was taken with warm water 2 h before exercise on training days, and supplemented on no
placebo group:4.7 g of sorbitol + ß-cyclodextrin per day was taken with warm water 2 h before exercise on training days and supplemented on non-training days using the same timing as on training days
Sponsors
School of Human Sports Science, Beijing Sport University
Eligibility
Sex/Gender
Male
Age
45 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Aged 45-65 years old; 2.Have more than five years of experience in marathon exercise prior to this study and have a regular running exercise frequency of at least 3 times per week; 3.Not taking any other cardiovascular disease-related medication or antioxidant in the three months prior to this study; 4. BMI of 18.5~23.9kg/m2.
Exclusion criteria
Exclusion criteria: 1. Having a clear contraindication to exercise or other medical condition that interferes with the exercise program; 2. Consumption of medications or supplements that may affect the experimental protocol; 3. Participation in a half marathon during the experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| creatine kinase;lactate dehydrogenase;myoglobin;Skeletal muscle troponin I;superoxide dismutase;Glutathione peroxidase;catalase;malondialdehyde;8-Hydroxydeoxyguanosine;4-Hydroxy-2-nonenal;reactive oxygen species; | — |
Secondary
| Measure | Time frame |
|---|---|
| height;weight;body mass index (BMI);Quiet heart rate;Quiet blood pressure;Visual Analog Scale;lactate clearance;Completion of simulated marathon time;Average heart rate after a simulated race;Simulates heart rate immediately after a race;Heart rate 15min after simulated race; | — |
Countries
China
Contacts
Public ContactYuan Mengjie; Guo Xian
Beijing Sport University
Outcome results
None listed