Chronic gingivitis, chronic periodontitis
Conditions
Interventions
experimental group:Use experimental toothpaste
control group:Use blank toothpaste
Sponsors
Stomatology Hospital Affiliated to Zhejiang Chinese Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1: patients with chronic gingivitis and chronic periodontitis who have been treated for 4 weeks 2: 18 to 70 years old. Women were not in pregnancy and lactation 3: no drugs affecting the test results 4: more than 20 detectable teeth, no open caries, mucosal lesions or moderate to severe periodontitis 5: obvious gingival redness, congestion, edema, probing or spontaneous bleeding, and gingival pockets and periodontal bags 3mm 6: not participating in other similar trials at the same time
Exclusion criteria
Exclusion criteria: 1: Systemic diseases, such as: hypertension, diabetes, coronary heart disease, immune disorders, mental disorders and other uncontrolled 2: Can not do morning and evening brushing 3: Those who cannot return to the clinic on time
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| bleeding index;plaque index;Detection of IL-1ß and TNF-a levels; | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of gingival crevicular fluid (GCF) content;Alkaline phosphatase (ALP) level detection; | — |
Countries
China
Contacts
Public ContactZheng Yuanna
School of Stomatology, Zhejiang Chinese Medical University
Outcome results
None listed