Cancer-related pain
Conditions
Interventions
experimental group:M1-tDCS anode true stimulation, 5 times a week, 20 minutes each time, for a total of 3 weeks
control group:M1-tDCS sham stimulation, only 20 minutes of stimulation for the first and last 30 seconds of stimulation, no actual effect, 5 times a week, 20 minutes each time, for a total of 3 weeks
Sponsors
The Sixth Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Be between the ages of 18-70; (2) Diagnosed with cancer requiring surgery and/or radiotherapy or chemotherapy; (3) Chief complainant of cancer-related pain for not less than 6 months; (4) Pain symptom severity score (Visual Analogue Score VAS) greater than or equal to 4 points.
Exclusion criteria
Exclusion criteria: (1) Combined with other chronic pain diseases such as fibromyalgia, low back pain, osteoarthritis pain, etc.; (2) Serious underlying diseases including gout, diabetes, coronary heart disease, hypertension, chronic kidney disease, progressive bleeding, cancer, central nervous system diseases such as stroke, cerebral hemorrhage, spinal cord injury, etc.; (3) Concomitant mental illness or abnormal mental status; (4) the presence of cognitive dysfunction; (5) There are contraindications to MRI examination, such as metal implants, dentures, pacemakers, etc.; (6) Received analgesic drug injection or analgesic pump implantation within the past 1 month; (7) Extremely severe cancer pain requires long-term dependence on morphine drugs, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain intensity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quantitative testing of central sensitization;Central Sensitization Scale;Quality of life assessment;Multimodal MRI brain imaging system; | — |
Countries
China
Contacts
Public ContactBeibei Feng
Department of Rehabilitation Medicine, The Sixth Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed