Bronchopulmonary dysplasia
Conditions
Interventions
Reactive group and non reactive group:None
Sponsors
Children's Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Neonates admitted to the NICU of Children's Hospital of Chongqing Medical University from July 1, 2024. Gestational age = 30 weeks. Birth weight = 1500g. Neonates required mechanical ventilation within the first week after birth and failed to wean. Neonates was treated with DART regimen of dexamethasone as clinically indicated from 1 week after birth. The patient's parents agreed to use dexamethasone DART after fully understanding the possible efficacy and risks of dexamethasone DART regimen and signed the informed consent for this study.
Exclusion criteria
Exclusion criteria: 1. Newborns with severe congenital heart disease, pulmonary malformation and other severe congenital malformation diseases. 2. Newborns die within 2 weeks after birth. 3. Newborns discharge or transfer to another hospital before PMA 36w.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Whether bronchopulmonary dysplasia was diagnosed;Severity of bronchopulmonary dysplasia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of invasive mechanical ventilation;Duration of noninvasive mechanical ventilation;Duration of oxygen supplement;Length of hospital stay;Whether neonatal necrotizing enterocolitis;Whether spontaneous bowel perforation;Whether level 3 and above intraventricular hemorrhage;Whether retinopathy; | — |
Countries
China
Contacts
Public ContactWang Jianhui
Children's Hospital of Chongqing Medical University
Outcome results
None listed