Age-related fertility decline in women
Conditions
Interventions
acupuncture group:acupuncture treatment
Sponsors
Sichuan Jinxin Xinan Women's and Children's Hospital
Eligibility
Sex/Gender
Female
Age
30 Years to 45 Years
Inclusion criteria
Inclusion criteria: (1) Age: 30= age =45 years, female; (2) Those who met both the DOR diagnostic criteria and those who were classified as having poor ovarian reserve function (=75 points) by the AAFA model of the OvaRePred prediction tool; (3) Regular menstrual cycle, i.e. (28±7) days; (4) Not participating in other ongoing clinical studies and not receiving acupuncture treatment targeting infertility in the last 3 months; (5) Informed consent signed by the patient herself or signed by her immediate family members on her behalf. Note: Subjects who also met the above 5 criteria were eligible for inclusion in this study.
Exclusion criteria
Exclusion criteria: (1) DOR caused by medical factors, such as pelvic surgery, radiotherapy or chemotherapy, uterine artery embolization, hormonal or immunosuppressive drugs; (2) Combination of other endocrine diseases that may affect reproductive function, such as polycystic ovary syndrome, hyperprolactinemia, hyperandrogenic individuals, thyroid disease, diabetes mellitus; (3) Combined with serious cardiovascular, cerebrovascular, hepatic, renal, malignant tumor, hematopoietic system diseases; (4) Combined with any mental illness; (5) Patients or partners with chromosomal abnormalities; (6) Patients with bleeding tendency and susceptibility to infection, or patients suffering from severe allergic diseases, or patients with skin ulcers or scarring that prohibit needling. (7) Those who are expected to have an in vitro program within 3 months of enrollment; Note: Any patient who meets any of the above criteria will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Scores and grading of the AAFA model, AFA model, and AA model in the Ovarian Reserve Assessment Calculator (OvaRePred).; | — |
Secondary
| Measure | Time frame |
|---|---|
| Self-Rating Anxiety Scale (SAS);Self-Rating Depression Scale (SDS);AMH;Serum sex hormone levels(FSH,E2,LH,P); | — |
Countries
China
Contacts
Public ContactYang Jie
Chengdu University of TCM;Sichuan Jinxin Xinan Women's and Children's Hospital
Outcome results
None listed