acute stroke
Conditions
Interventions
medical management group:NA
Sponsors
Sichuan Mianyang 404 Hospital (Mianyang First People's Hospital)
Eligibility
Sex/Gender
All
Age
No minimum to 100 Years
Inclusion criteria
Inclusion criteria: (1) Diagnosed as acute ischemic stroke based on clinical symptoms or imaging examination; (2) The interval from the onset of the disease or the last normal time to the start of treatment is greater than 24 hours; (3) CTA/MRA/DSA clearly indicates occlusion of the internal carotid artery, middle cerebral artery M1 or M2 segment, or vertebrobasilar artery; (4) The patient or family member signs a written informed consent form.
Exclusion criteria
Exclusion criteria: (1) Confirmed intracranial hemorrhage by CT or MRI; (2) Brain herniation and midline deviation; (3) Previous hemorrhagic diseases, severe heart, liver or kidney diseases, or sepsis; Late stage of any disease results in an expected lifespan of less than 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 90-day modified Rankin scale score ; | — |
Secondary
| Measure | Time frame |
|---|---|
| 90-day modified Rankin scale score of 0-1;90-day modified Rankin scale score of 0-3;NIHSS score at 5-7 days postoperatively;The success rate of perfusion at the end of intravascular treatment (defined as eTICI score=2b);Incidence of symptomatic intracranial hemorrhage within 48 hours (according to Heidelberg typing criteria);Incidence of any intracranial hemorrhage within 48 hours;Incidence of non-intracranial hemorrhage complications (bleeding from the oral cavity, gastrointestinal tract, urinary tract, etc.);Mortality within 90 days;Operative and device-related complications (including arterial rupture, arterial entrapment, implantation failure, stent fracture, vascular puncture point complications, vasospasm, and device failure);Incidence of non-hemorrhagic serious adverse events (including brain herniation, pneumonia, respiratory failure, circulatory failure, stress ulcers, secondary epilepsy, urinary tract infections, sepsis, renal failure, acute coronary syndromes, venous thrombosis, and psychiatric symptoms); | — |
Countries
China
Contacts
Public ContactJun Luo
Sichuan Mianyang 404 Hospital (Mianyang First People's Hospital)
Outcome results
None listed