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Effect of maternal body mass index on the prophylactic dose of metaraminol for preventing hypotension in parturients after spinal anaesthesia

Effect of maternal body mass index on the prophylactic dose of metaraminol for preventing hypotension in parturients after spinal anaesthesia

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400086366
Enrollment
Unknown
Registered
2024-06-29
Start date
2024-07-01
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypotension in cesarean section

Interventions

Standard group (group S, BMI 30 kg/m2):Between hydroxylamine initial dose were selected to 2 mg, mass concentration of 0.02 mg/mL, at a fixed rate of 100 mL/h infusion, according to former between wh

Sponsors

Suzhou Municipal Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Full-term women aged 18-35 yr with singleton pregnancyscheduled for elective Caesarean delivery.

Exclusion criteria

Exclusion criteria: ASA physical status >= 3, obesity (BMI > 30kg·m-2), height < 150cm , early or active labour, pre-existing or pregnancy-induced hypertension, diabetes mellitus, significant cardiovascular or cerebrovascular disease, known fetal abnormality, intrauterine growth restriction, obstetric complication (ruptured membranes, placenta praevia, placental abruption), and any contraindication tospinal or epidural an

Design outcomes

Primary

MeasureTime frame
hypotension;

Secondary

MeasureTime frame
Umbilical artery blood pH;umbilical vein blood PH;umbilical artery blood partial pressure of oxygen;umbilical vein blood partial pressure of oxygen;umbilical artery blood BE;umbilical vein blood BE;umbilical artery blood HCO3-;umbilical vein blood HCO3-;fetal Apgar score (1 minute and 5 minutes after birth);The incidence of nausea in pregnant women;The incidence of vomiting in pregnant women;

Countries

china

Contacts

Public ContactLei Wei

Suzhou Municipal Hospital

64624369@qq.com+86 138 1487 4405

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 14, 2026