Postoperative nausea and vomiting
Conditions
Interventions
Ciprofol group:Anesthesia induction using 0.4mg/kg ciprofol,with a maintenance dose of 0.8-2mg/kg/h of ciprofol during surgery
Sevoflurane group:Application of 2mg/kg propofol for anesthesia induction,maintained with sevoflurane during surgery,MAC 0.7-1.0
Propofol group:Application of 2mg/kg propofol for anesthesia induction,with a maintenance dose of 4-12mg/kg/h of propofol during surgery
Sponsors
Baoding First Central Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Selective general anesthesia for gynecological laparoscopic surgery; 2.Age 18-60 years old; 3.BMI 18~30kg/m2; 4.ASA Level ?~?; 5.Surgical time 2-4 hours.
Exclusion criteria
Exclusion criteria: 1.Patients with a history of motion sickness,Meniere's syndrome,or otolithiasis; 2.Drug and alcohol abuse patients; 3.Patients who have received radiotherapy and chemotherapy within 7 days before surgery; 4.Patients with a history of severe systemic diseases and drug allergies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of nausea and vomiting within 24 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of postoperative nausea and vomiting;The use of rescue anti-emetic drugs;Hemodynamic changes during tracheal intubation and extubation; | — |
Countries
China
Contacts
Public ContactFan Huang
Baoding First Central Hospital
Outcome results
None listed