Skip to content

Clinical multiple centers study of acellular dermal matrix for multipoint periodontal soft tissue augmentation

Clinical multiple centers study of acellular dermal matrix for multipoint periodontal soft tissue augmentation

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400086341
Enrollment
Unknown
Registered
2024-06-28
Start date
2024-07-01
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gingival recession, soft tissue deficiency

Interventions

test group:using ADM graft to augment soft tissue in gingival recession teeth
control group:using CTG graft to augment soft tissue in gingival recession teeth

Sponsors

Stomatological Hospital Affiliated to Medical College of Zhejiang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1)Patients with none systemic disease and age over 18 years old; 2)Patients with labial-buccal RT type 1 or 2 gingival regression with thin phenotype and at least three teeth.

Exclusion criteria

Exclusion criteria: 1) Patients with heavy smoking, smoking more than 10 cigarettes per day; 2) Pregnant or lactating women; 3) Untreated periodontal disease; 4) Existing systemic diseases affecting wound healing; 5) Presence of cervical caries or non-caries lesions or cervical prosthetics; 6) Taking immunosuppressants or hypertension drugs affects wound healing; 7) Radiotherapy; 8) Collagen allergy; 9) Existing early contact and other occlusal trauma or dental irregularities requiring orthodontic treatment.

Design outcomes

Primary

MeasureTime frame
Gingival recession depth;KTW;gingival thickness;

Secondary

MeasureTime frame
Probing depth;root coverage aesthetic index;

Countries

China

Contacts

Public ContactWei Lu

Affiliated Stomatology Hospital of Zhejiang University

jocelyn1016@zju.edu.cn+86 137 3817 3694

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026