type 2 diabetes
Conditions
Interventions
Low carbon dietary intervention:Low carbon dietary intervention
intestinal flora reconstruction:intestinal flora reconstruction
Low carbon dietary with intestinal flora reconstruction intervention:Low carbon dietary with intestinal flora reconstruction
Conrol:Diet for diabetes, maintain the existing hypoglycemic program and adjust the type and dosage of drugs appropriately according to the level of blood glucose
Sponsors
Huashan Hospital Fudan University
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: Voluntarily participate, understand the intervention process and sign an informed consent form; ? Type 2 diabetes is diagnosed, the first diagnosis or the course of disease is short (within 10 years), and the general condition is good; Age range from 40 to 70 years old; Glycated hemoglobin>8.0% BMI>26kg/m2; If study participants are taking metformin or alpha glucosidase inhibitors during screening, they must have been using a stable dose for at least 4 weeks before the start of the study.
Exclusion criteria
Exclusion criteria: ? Type 1 diabetes, special type diabetes, etc; ? Type 2 diabetes patients with serious chronic complications; ? Acute complications of diabetes, such as diabetes ketoacidosis, hypoglycemia, hypertonic state, etc; HbA1c = 15%, or fasting blood glucose = 15 mmol/L; ? diabetes patients who are using SGLT-2 inhibitor; Recent gastrointestinal bleeding; Cirrhosis, esophageal and gastric varicose veins; Repeated intestinal obstruction with extensive intestinal adhesions; Patients with acute or subacute stroke, difficulty swallowing, and coughing due to drinking water; Patients who undergo colostomy after intestinal surgery; Other serious systemic diseases or infections, such as severe cardiopulmonary insufficiency, lung infections, etc; Pregnant and lactating women; Participants in other clinical trials during the same period; Individuals who are unable to persist in intervention due to various reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glycated albumin; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fasting plasma glucose;HbAlc; | — |
Countries
China
Contacts
Public ContactRenming Hu
Huashan Hospital Fudan University
Outcome results
None listed