chronic postsurgical pain
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Chinese Han ethnicity, right-handed, aged 18-80 years, ASA class I-III; (2) Undergoing elective surgery for non-malignant pancreatic occupying lesions.
Exclusion criteria
Exclusion criteria: (1) History of chronic pain and long-term use of analgesics and/or sedatives before surgery; (2) Dependence on drugs, substances, alcohol, or tobacco; (3) History of head trauma or neurosurgery; (4) Patients with central nervous system disorders and psychiatric disorders; (5) Known chronic diseases that can induce encephalopathy; (6) Presence of malignant tumors in other parts of the body; (7) Contraindications to surgery or MRI examinations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence and severity of chronic postoperative pain;Functional magnetic resonance imaging metrics;Structural magnetic resonance imaging metrics; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence and severity of acute postoperative pain;Delirium and postoperative cognitive dysfunction;Postoperative anxiety and sleep quality;Intraoperative and postoperative sedation and analgesic drug dosages;Postoperative complications; | — |
Countries
China
Contacts
Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School