recovery
Conditions
Interventions
0.2mg Flumazenil group:After operation, 0.2mg of flumazenil was used
0.5mg Flumazenil group:After operation, 0.5mg of flumazenil was used
1.0mg Flumazenil group:After operation, 1.0mg of flumazenil was used
0.9%NACI:Use normal saline after surgery
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Candidates for elective ERCP; 2) American Society of Anesthesiologists (ASA) Grades II to III; 3) Age 65-80 years old; 4) Body Mass index (BMI) : 18.5 ~ 23.9kg/m^2; 5) Able to complete Chinese PQRS.
Exclusion criteria
Exclusion criteria: 1) Chronic alcoholism or treatment with narcotic analgesics, sedatives, and antidepressants; 2) Have a history of psychiatric disorders (such as seizures) or cerebrovascular diseases; 3) Patients with obvious abnormal liver and kidney function: Child-Pugh grade C or blood creatinine (Scr) > 451µmol/L or blood urea nitrogen (BUN) > 17.9mmol/L; 4) Severe auditory and visual impairment, poor communication ability; 5) Patients who are allergic to medications such as flumazenil or remazolam or who refuse to participate. 6) Patients who temporarily change the mode of surgery or anesthesia; 7) Patients receiving other sedative supplements (cyclopofol); 8) The operation duration is too long or too short (> 90min or < 20min).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| open eyes time;PQRS; | — |
Secondary
| Measure | Time frame |
|---|---|
| time to activity recovery;awake time;time to arrive get out PACU;complication; | — |
Countries
China
Contacts
Public ContactZhu Yunsheng
The First Affiliated Hospital of Nanchang University
Outcome results
None listed