patients that need for anticoagulation therapy
Conditions
Interventions
NOACs monotherapy group:None
Herb-NOACs combination group:None
Sponsors
Beijing Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) the clinic patients need for anticoagulation with NVAF, venous thromboembolism, pulmonary embolism, etc.; (2) age >= 18 years old, male or female; (3) NOACs group (control group) or target herb and NOACs combination group (exposure group) were treated for 3-6 months; (4) the patient is willing and able to cooperate to accept follow-up.
Exclusion criteria
Exclusion criteria: (1) patient with combined immunodeficiency diseases; (2) patient has a history of chronic liver disease, hepatitis b surface antigen and/or hepatitis c antibody positive; (3) NOACs taboo certificate (including severe liver and kidney function was abnormal, blood coagulation was abnormal, obvious active bleeding, bleeding, significant risk lesions or disease, severe hypertension, anticoagulants with healers, pregnant women and nursing mothers); (4) NOACs within 14 days before treatment used potent CYP3A4 inhibitors and/or P - gp inhibitors, potent CYP3A4 inducers and/or P - gp inducers; (5) unable to obtain the necessary clinical data; (6) There were other conditions that the researchers considered inappropriate for participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Outcome events: including bleeding events (including major bleeding, clinically relevant non major bleeding, minor bleeding), stroke/systemic embolism events; | — |
Countries
China
Contacts
Public ContactPengfei Jin
Beijing Hospital
Outcome results
None listed