Skip to content

A study on the impact of epidural analgesia during latent period on labor process and its analgesic effect

A study on the impact of epidural analgesia during latent period on labor process and its analgesic effect

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400086270
Enrollment
Unknown
Registered
2024-06-27
Start date
2024-07-01
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

none

Interventions

Nabupine+Epidural Group:Immediately administer 5mg of nalbuphine (diluted to 10ml), place the analgesic pump in an opaque black cloth bag, turn on the analgesic pump in the epidural group, and tempora
Epidural Group:Immediately administer 0.9% sodium chloride 10ml intravenously, insert the analgesic pump into an opaque black cloth bag, turn on the analgesic pump, and the mother presses the analgesi

Sponsors

Affiliated Xiaoshan Hospital of Hangzhou Normal University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1.Primiparous women aged 18 to 40 years old; 2.ASA II 3.Height = 150 cm, 50kg = Weight = 100 kg; 4.Gestational age (37-42 weeks); 5.Obstetricians evaluate that vaginal delivery is possible and there is a need for epidural analgesia during delivery, with a cervix smaller than 3cm.

Exclusion criteria

Exclusion criteria: 1.Allergy to the drugs used in this study; 2.Twin or multiple pregnancies; 3.Complicated with gestational diseases (such as pre eclampsia, gestational diabetes, etc.); 4.Maternal refusal and other situations. 5.contraindications for epidural analgesia a.Those who are unable to cooperate with the mother (such as psychiatric patients: during the onset of mental illness; severe neurosis, etc.) b.Patients with sepsis, systemic suppurative or purulent infections, and those with infections or tumors at the puncture site that are not suitable for spinal puncture. c.Central nervous system disorders (meningoencephalitis, poliomyelitis, elevated intracranial pressure, and severe headache) d.Spinal deformities (located in the lower back), hidden spina bifida, intervertebral disc herniation, history of spinal stenosis, spinal tumors, and history of spinal surgical trauma. e.Individuals with abnormal coagulation function and long-term oral anticoagulant medication. f.Blood routine platelet count is less than 80 * 10 ^ 9/L22. 6. Failure of epidural catheterization, with blood, cerebrospinal fluid, etc. being withdrawn.

Design outcomes

Primary

MeasureTime frame
First production process time;

Secondary

MeasureTime frame
1% lidocaine relieves the number of cases of explosive pain;PCEA parameters: total drug consumption, total number of compressions, effective number of compressions;;Vital signs of postpartum women;Anesthesia sensation plane;Pain score;Assessment of sedation level;Motor block score;The usage of Nabupine Injection (dosage, frequency);The use of oxytocin (dosage, frequency);General information of postpartum women;Newborns 1 and 5 minute Apgar score;;Delivery type;Second production process time, total production process time;

Countries

China

Contacts

Public ContactYu Jing

Affiliated Xiaoshan Hospital of Hangzhou Normal University

yujing7274@126.com+86 189 6716 8531

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026