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The mechanism of RNA-binding protein STAU1-mediated SMD pathway involved in COPD oxidative stress by regulating PPAR?

The mechanism of RNA-binding protein STAU1-mediated SMD pathway involved in COPD oxidative stress by regulating PPAR?

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400086268
Enrollment
Unknown
Registered
2024-06-27
Start date
2024-07-01
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic obstructive pulmonary diseases

Interventions

Healthy group:none

Sponsors

People's Hospital of Xinjiang Uygur Autonomous Region
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) COPD patients diagnosed with objective evidence; The GOLD group is group E. 2) Normal cognitive ability; 3) Be familiar with this study, volunteer to participate, and sign informed consent.

Exclusion criteria

Exclusion criteria: 1) Combined with other lung diseases, including bronchial asthma, bronchiectasis, pulmonary fibrosis, pulmonary malignancy and other airflow limited diseases; Tuberculosis or receiving antiseptic chemotherapy for tuberculosis; Within 1 month after healing of severe pulmonary bulla, pneumothorax and pneumothorax; 2) Have a history of lung surgery; 3) Severe physical or mental illness, including unstable angina pectoris, history of myocardial infarction within 3 months, uncontrolled hypertension or hypertensive crisis, heart valvular disease, thoracoabdominal aortic aneurysm, uncontrolled cardiac insufficiency, severe liver insufficiency, renal failure, malignant tumor, etc.; 4) Pregnant women or breastfeeding women; 5) Unwilling to participate or unable to cooperate.

Design outcomes

Primary

MeasureTime frame
Staufen1;peroxisome proliferators-activated receptors ? ;Upframe shift 1;p-Upframe shift 1;Lung function;

Countries

China

Contacts

Public ContactZhang Ling

People's Hospital of Xinjiang Uygur Autonomous Region

1713864230@qq.com+86 177 9979 7912

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026