Skip to content

Correlation between 25-(OH)-D and ovarian reserve function based on vitamin D metabolism and the modulating effect of the classic formula of Guilu Erxian Ointment combined with Wuzi YanZong Pill

Correlation between 25-(OH)-D and ovarian reserve function based on vitamin D metabolism and the modulating effect of the classic formula of Guilu Erxian Ointment combined with Wuzi YanZong Pill

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400086264
Enrollment
Unknown
Registered
2024-06-27
Start date
2024-07-01
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diminished ovarian reserve

Interventions

VD group:VD combined with estrogen-progestin sequential therapy
control group:estrogen-progestin sequential therapy
Erwu Hefang group:Erwu Hefang combined with estrogen-progestogen sequential treatment

Sponsors

Provincial Hospital of Shandong First Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: a. 18 years old = age < 40 years old; b. Meet the criteria of Western medicine diagnosis and Chinese medicine identification; c.Not taking estrogen-progestogen drugs in the last three months; d. Good compliance and voluntary cooperation to complete the treatment.

Exclusion criteria

Exclusion criteria: a. Poor compliance and inability to cooperate in completing the treatment; b.Combined with other endocrine diseases such as hyperprolactinemia and abnormal thyroid function; c.Congenital or acquired malformation of reproductive organs; d.Those who suffer from major cardiovascular and cerebrovascular diseases, mental diseases or malignant tumors; e.Those who take other medication that may affect the evaluation of efficacy; f. Those with abnormal liver or kidney function, abnormal coagulation function and other diseases.

Design outcomes

Primary

MeasureTime frame
25-(OH)-D;VDR;CYP2R1;

Secondary

MeasureTime frame
FSH;Basal antral follicle count;Kidney deficiency syndrome scores;LH;E2;AMH;

Countries

China

Contacts

Public ContactPingping Cai

Provincial Hospital of Shandong First Medical University

pingpingcai@126.com+86 151 6888 7651

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026