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Functional connection-guided individualized transcranial magnetic stimulation of the left dorsolateral prefrontal lobe for the treatment of chronic insomnia disorder

Functional connection-guided individualized transcranial magnetic stimulation of the left dorsolateral prefrontal lobe for the treatment of chronic insomnia disorder

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400086249
Enrollment
Unknown
Registered
2024-06-27
Start date
2024-07-01
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic insomnia disorder

Interventions

Chronic insomnia disorder group:Individualized precision targeting repetitive transcranial magnetic stimulation
Healthy control group:None

Sponsors

Inner Mongolia Mental Health Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) Meet the diagnostic criteria for chronic insomnia disorders in the International Classification of Sleep Disorders, 3rd Edition (ICSD-3); (2) Pittsburgh sleep quality index (PSQI) score greater than or equal to 7 points before treatment; (3) Age 18-65 years old, right-handed; (4) Adequate understanding ability, education level = 6 years; (5) Understand the research content and sign the informed consent. (6) Have no history of drug treatment, or have a history of drug treatment or are currently on drug treatment, but still meet the above criteria.

Exclusion criteria

Exclusion criteria: (1) Abusers of alcohol, drugs or other psychoactive substances; (2) Pregnant or lactating women; (3) Past and current central nervous system diseases and other serious physical diseases; (4) Secondary insomnia caused by physical illness, drug dependence or schizophrenia; (5) HAMD-17 score = 17 points; (6) Contraindications to TMS; (7) MRI contraindications.

Design outcomes

Primary

MeasureTime frame
Functional connection;

Secondary

MeasureTime frame
Local activity index;Pittsburgh Sleep Quality Index Scale;Insomnia severity index scale;17 items Hamilton Depression Scale;Hamilton anxiety scale;Number symbol substitution test;

Countries

China

Contacts

Public ContactYating Shi

Inner Mongolia Mental Health Center

31308903@qq.com+86 186 0488 6648

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026