Traumatic stress disorder after spontaneous abortion
Conditions
Interventions
Research group:Oral contraceptive pills
Control group:None
Sponsors
Women‘s Hospital School of Medicine Zhejiang University
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1: Women aged 18-40 with a history of spontaneous abortion and fertility requirements; 2: Spontaneous miscarriage gestational age <= 10 weeks 3: Complete natural abortion or choosing artificial abortion to terminate pregnancy due to inevitable abortion; 4: Willing to accept short-term oral contraception treatment after natural abortion, and able to cooperate with research for follow-up and data collection; 5: Willing to implement instrumental contraception simultaneously during the research period; 6: No contraindications for short acting oral contraceptives, such as liver disease, kidney disease, cardiovascular disease, cerebrovascular disease, etc; 7: Having no prior history of mental illness or mental illness, able to independently complete the psychological health assessment required for the study; 8: No severe allergic reactions or drug intolerance, able to tolerate the side effects caused by short acting oral contraceptives.
Exclusion criteria
Exclusion criteria: (1) Long term or current short-term oral contraceptive users; (2) Subjects with hormone dependent diseases or adverse reactions to short acting oral contraceptives; (3) Subjects with a history of severe mental illness or current mental illness; (4) Diagnosed with PTSD and severe symptoms, assessed by a psychiatrist as requiring psychiatric drug control; (5) During the research period, it was not allowed to use contraception tools according to regulations; (6) Subjects with contraindications to the research process or short acting oral contraceptives; (7) Subjects who are unable to cooperate in completing the study or unable to comply with the study regulations;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement rate of anxiety/depression; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum sex hormone levels: estradiol (E2, pmol/L), follicle stimulating hormone (FSH, IU/L), serotoni;The incidence rate of incomplete miscarriage ;The time of menstruation relapse (days); | — |
Countries
China
Contacts
Public ContactJiang Xiuxiu
Women‘s Hospital School of Medicine Zhejiang University
Outcome results
None listed