Rebound pain after peripheral nerve block
Conditions
Interventions
lidocaine group :After the nerve block is administered, receive a continuous intravenous infusion of lidocaine at 2 mg/kg/h.
placebo group:After the nerve block is administered, intravenous injection of physiological saline at an equal rate
Sponsors
Central Hospital of Dalian University of Technology
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Patients between 18 and 70 yr of age.2.ASA I–III.3.Patients with an upper limb fracture undergo elective surgery under brachial plexus block anesthesia.
Exclusion criteria
Exclusion criteria: 1.refused to participate in research; 2.allergy to lidocaine and ropivacaine 3.coagulation disorders, neuropathic and psychiatric disorders, diaphragmatic paralysis,severe cardiopulmonary disease,cardiac conduction block, pregnancy,severe obesity (body mass index>35 kg/m2) 4.systemic steroid use,any chronic pain and opioids abuse 5.an inability to understand pain scoring or the instructions forintravenous patient-controlled analgesia (PCA);6. a failed brachial plexus block; 7.patients with any residual numbness after 24 hours and with definite peripheral nerve injury,patients do not receive a single injection of nerve block.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of rebound pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| The severity of rebound pain score, the onset and duration of rebound pain;PNB effective analgesic time;Consumption of additional opioid drugs (converted to morphine equivalent if different types);Sleep disorders and possible complications;Overall patient satisfaction with pain control;Has the patient experienced severe pain and/or sleep disorders after discharge, and will they choose nerve block again in the future; | — |
Countries
China
Contacts
Public ContactLi Wang
Central Hospital of Dalian University of Technology (Dalian Central Hospital)
Outcome results
None listed