To explore the molecular characteristics of acupuncture in the treatment of primary insomnia based on multimodal magnetic resonance brain functional connection group and serum metabolism group.

Study on the Neural Mechanism of Acupuncture and moxibustion in the treatment of Primary Insomnia based on Multimodal MRI brain function connection Group and Serum Metabolism Group

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400086190

Enrollment

Unknown

Registered

2024-06-26

Start date

2024-07-01

Completion date

Unknown

Last updated

2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Insomnia

Interventions

Primary insomnia group:Acupuncture treatment for one month

Heathy adult control group:NONE

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: a. Meet the diagnostic criteria of DSM-V for primary insomnia; b. PSQI > 7 points; c. No history of taking anti-anxiety, depression or sleep medications in the past two weeks; d. Exclude other mental disorders and systemic organic diseases; e. No serious skin or blood-related diseases, such as neurodermatitis and atopic dermatitis, thrombocytopenia, coagulation disorders and hemophilia; f. Able to accept the treatment of this study, not fainting or afraid of acupuncture, and able to cooperate with doctors to complete data collection before and after treatment; g. Patients who have informed consent to participate in this project and are willing to participate in the enrollment and can actively cooperate.

Exclusion criteria

Exclusion criteria: a. Other sleep disorders caused insomnia: b. Such as sleep apnea syndrome, narcolepsy, restless leg syndrome, etc.; c. Has suffered from serious heart, brain, liver, kidney disease or other serious physical diseases; d. The patient has a history of brain injury or brain surgery; e.MRI scanning contraindications (e.g. metal in the body, pacemaker installation, claustrophobia); f. History of other mental illness or family history; g. History or current history of alcohol and drug abuse; h. Pregnant or lactating women; i. Unqualified brain function data.

Design outcomes

Primary

Measure	Time frame
Pittsburgh Sleep Quality Index scale score;Voxel-Mirrored Homotopic Connectivity(VMHC);	—

Secondary

Measure	Time frame
Insomnia severity index, ISI;	—

Countries

China

Contacts

Public Contactliting

Peace Hospital affiliated to Changzhi Medical College

liting@czmc.edu.cn+86 152 0355 0055

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026