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Effect of Pulmonary Recruitment Maneuver combined with controlled hyperventilation on laparoscopic postoperative shoulder pain

Effect of Pulmonary Recruitment Maneuver combined with controlled hyperventilation on laparoscopic postoperative shoulder pain

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400086185
Enrollment
Unknown
Registered
2024-06-26
Start date
2024-07-01
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

laparoscopic postoperative shoulder pain

Interventions

Pulmonary Recruitment Maneuver combined with controlled hyperventilation group:PETCO2 was maintained at 30-34 by adjusting tidal volume, respiratory rate and inspiratory/expiratory ratio immediately a
Pulmonary Recruitment Maneuver group: After the end of laparoscopic surgery, lung recruitment maneuvers were performed 6 times (APL valve pressure was 40cm H20) for 5 seconds each time.
controlled hyperventilation group:PETCO2 was maintained at 30-34 by adjusting tidal volume, respiratory rate and inspiratory/expiratory ratio immediately after intubation.
control group:conventional passive exhaust method was used to expel residual CO2 (gentle pressure on the abdomen) + conventional mechanical ventilation to maintain PETCO2 at 35-45.

Sponsors

Affiliated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. The elective patients with gynecological surgery; 2.ASA grade ?-?; 3.18-65 years old; 4.BMI 18-30kg/?.

Exclusion criteria

Exclusion criteria: 1. Combined with chronic diseases such as scapulohumeral periarthritis and cervical spondylosis; 2. Preoperative have nausea and vomiting; 3. History of chest and shoulder surgery; 4. Pregnancy; 5. Decompensated heart disease (heart failure, myocardial infarction, severe arrhythmia); 6. Severe respiratory disease (severe obstructive or restrictive lung disease, respiratory failure, pneumothorax or emphysema); 7. Severe liver dysfunction (serum total bilirubin 2 mg/dl or higher); 8. Severe renal dysfunction (glomerular filtration rate < 60ml/ (min·1.73m2); 9. Had cognitive dysfunction before surgery and could not cooperate to complete the visit; 10. Recent use of non-steroidal analgesics; 11. The central nervous system disease; 12. Previous cerebral infarction.

Design outcomes

Primary

MeasureTime frame
incidence of shoulder ache and VAS score;

Secondary

MeasureTime frame
Duration of postoperative shoulder soreness;Abdominal pain score (incision pain score and visceral pain score);Recovery of 48 h of 15 quality rating scale score (QoR - 15);Nausea and vomiting;The first postoperative exhaust time;Pulmonary complications (, pleural effusion, atelectasis, pneumothorax, etc.);Other complications (subcutaneous emphysema, etc.);Duration of anesthesia;Duration of pneumoperitoneum;Intraoperative consumption of remifentanil;Intraoperative consumption of sufentanil;Intraoperative infusion quantity;Intraoperative urinary volume;The end of the lung function (before pneumoperitoneum, pneumoperitoneum dynamic lung compliance);Consumption of remedial analgesics within 24 hours;Intraoperative hemodynamic changes in tidal volume, the airway peak pressure, breath at the end of the co2 partial pressure (PETCO2), intraoperative pneumoperitoneum pressure;The pH after and before pneumoperitoneum pneumoperitoneum, PaCO2, PaO2;

Countries

China

Contacts

Public ContactGuanglei Wang

Affiliated Hospital of Xuzhou Medical University

wanglx0312@163.com+86 138 5208 7156

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026