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Cuxing acupuncture combined with repetitive transcranial magnetic stimulation promotes functional reorganisation of brain regions in patients with minimal conscious state

Cuxing acupuncture combined with repetitive transcranial magnetic stimulation promotes functional reorganisation of brain regions in patients with minimal conscious state

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400086163
Enrollment
Unknown
Registered
2024-06-26
Start date
2024-06-26
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Minimal state of consciousness after stroke

Interventions

experimental group:Cuxing acupuncture combined with repetitive transcranial magnetic stimulation
control group1:Cuxing acupuncture
control group2:repetitive transcranial magnetic stimulation

Sponsors

Guangdong Second Traditional Chinese Medicine Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: ?Conform to the diagnostic criteria of stroke and the most conscious state.The diagnostic criteria of cerebral infarction and cerebral hemorrhage will be referred to "Diagnostic Highlights of Various Major Cerebrovascular Diseases in China 2019".The diagnostic criteria of the minimal conscious state will be referred to "The 2018 edition of the American Practice Guide for Disorders of Consciousness". ?Aged 18-70 years, regardless of gender. ?Consciousness disorder caused by non-other reasons. ?Written informed consent. ?Duration of impaired consciousness less than 6 months.

Exclusion criteria

Exclusion criteria: ?Those who have participated in other research projects in the last 3 months. ?Patients with unstable vital signs ( blood pressure, respiration, pulse ) or with active cerebral hemorrhage. ?Complicated with serious heart, lung, liver and kidney complications. ?Those who don't receive acupuncture treatments. ?Those who are not suitable for magnetic resonance examination because of metal foreign objects in the body, such as coronary stent implantation and pacemaker implantation. ?Women in lactation.

Design outcomes

Primary

MeasureTime frame
Glasgow Coma Scale;Coma Recovery Scale-Revised;central nervous system-specific protein (S-100ß);

Secondary

MeasureTime frame
neuron-specific enolase (NSE);functional magnetic resonance imaging;

Countries

China

Contacts

Public ContactXi Wen

Guangdong Second Traditional Chinese Medicine Hospital

21wenc@21cn.com+86 138 2608 2632

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026