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Effect of Kangfuxin solution on preventing adverse events of endoscopic mucosal resection for colorectal adenoma: a randomized controlled trial

Effect of Kangfuxin solution on preventing adverse events of endoscopic mucosal resection for colorectal adenoma: a randomized controlled trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400086147
Enrollment
Unknown
Registered
2024-06-26
Start date
2024-07-01
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal adenoma

Interventions

Group A:After the operation, Kangfuxin solution (10ml/ time, three times a day, oral) was routinely taken for 7 days. If the patient can not tolerate it, then stop the Kangfuxin solution.
Group B:No Kangfuxin solution was taken after surgery.

Sponsors

Shenzhen People's Hospital (the Second Clinical Medical College of Jinan University, the First Affiliated Hospital of South University of science and Technology)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: ?Patients aged 18-80 years, male and female;?patients with colorectal adenoma (10mm=d=20mm) and received EMR treatment;?patients who sign the written informed consent;?the specimen was confirmed with adenomatous polyp by pathology.

Exclusion criteria

Exclusion criteria: ?Patients with abnormal colorectal anatomy and could not complete endoscopic surgery;?patient with colorectal adenoma with diameter less than 10mm or larger than 20mm;?pregant women;?severe heart, liver, and kidney dysfunction;?patients with coagulation dysfunction;?other identifiable causes of infection, fever, and elevated WBC, such as pneumonia;?allergic to drug ingredients;?patients with inflammatory bowel disease, Crohn's disease, familial polyps, and those who were not considered suitable for participants by the researchers.

Design outcomes

Primary

MeasureTime frame
bleeding;perforation;abdominal pain;fever;elevated white blood cells;

Secondary

MeasureTime frame
procedure duration;

Countries

China

Contacts

Public ContactJun Yao

Shenzhen People's Hospital (the Second Clinical Medical College of Jinan University, the First Affiliated Hospital of South University of science and Technology)

yao.jun@szhospital.com+86 159 1409 5696

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026